The Donor/Recipient concept goes as follows: Book An Appointment What Are Blood Types and Transfusion? Hence, it is compatible with every other blood group of the ABO and Rh system. If present, the blood group is called RhD+ (positive), and if absent, it is RhD- (negative).Īs mentioned earlier, the O- blood type can be safely given to any person with any blood type since it does not contain any A, B, or RhD antigens on the surface of the red blood cells. The most significant Rh antigen is the D antigen because it is the most likely to provoke an immune system response of the five main Rh antigens. Rh, meaning Rhesus system, contains 49 blood group antigens, out of which five are most significant. Rh SystemĪpart from the ABO system, there is another system to determine a person’s blood group. Similarly, AB type is a universal recipient since it does not have any antibodies present in order to attack antigens. This also explains why O type is a universal donor since it has no antigens present in the first place to be attacked by antibodies. If the antigen and antibodies are not similar, the antibody will attack the antigen as a defensive action by the immune system. Agglutination means the clumping of particles. Hence, during blood transfusions, an agglutination reaction occurs between similar antigen and antibody. It includes Type A, B, AB, and O.Īntigens and Antibodies play a crucial role in determining a person’s blood type. The ABO blood group system defines four main blood groups. Therefore, cross-matching and correct blood-typing are critical. Some antigens can make your immune system consider the transfused blood as a foreign body and attack it. It is crucial to ensure that the blood type of the donor and recipient are matching when it comes to blood transfusions. Simply put, the people with type O negative blood are universal red cell donors, and people with type AB blood group are universal plasma donors. Antibodies are our natural defense mechanisms and are produced by the immune system when there is exposure to a foreign antigen. Antibodies bind specifically to the corresponding antigen on the red blood cells. Antibodies are protein molecules called Immunoglobulins (Ig) found in plasma. Our blood contains red blood cells, white blood cells, and platelets in a liquid called plasma.Īntigens are molecules found on the surfaces of the red blood cells and contain protein and carbohydrates. The blood type or the blood group is a form of classification of blood that depends on the presence and absence of antibodies and inherited antigens on the surface of red blood cells. Which Blood Group Types Are Universal Donors? It is vital to know a person’s blood type in case of emergencies or if there is a need for a blood transfusion. Among these 38 systems, the ABO and Rh are the most widely used. The International Society of Blood Transfusion (ISBT) recognizes 38 human blood group systems. Depending on these factors, the blood type can be A+, A-, B+, B-, O+, O-, AB+ or AB. Besides this, the presence or absence of the Rh factor, a protein, determines if your blood group would be negative or positive. The presence of antigens A&B on the surface of RBCs decides the four main blood groups. The blood contains red blood cells, white blood cells, and platelets in plasma – a liquid in the blood. The antigen helps trigger the immune system if any foreign body enters the bloodstream and produces antibodies to fight it. How is the Blood type determined?īlood groups are determined by the presence and absence of antigens in the blood. However, about 7% of people have an O-negative blood type, and about 37% of the population has an O-positive blood type, making it a common blood group. The blood group type O (positive and negative) is in high demand due to its need during emergencies. A person with blood group O+ (positive cells) cannot give blood to an Rh-negative individual. So, they can donate blood to any other blood group. It is because their red blood cells do not carry antigens. More About a Universal Blood DonorĪlthough people with an O blood type are commonly known as universal blood donors, people with O- (negative) blood type are the true universal donors. This blood group barely causes any reactions to the recipient and is called a universal donor blood group. In such cases, a person with group O, specifically O negative, can donate blood to the patient. In some emergencies, donors with the same blood group as the patient may not be available. A universal donor is a person who can donate blood to any recipient of any blood group.
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